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  Cardiovascular Risk Assessment in Men (10-year, Reynolds Risk Score 2008) and Optimization

 
Terms = (4.385 * ln(Age)) + (2.607 * ln(SystolicBloodPressure)) + (0.963 * ln(TotalCholesterol)) - (0.772 * ln(HDLCholesterol)) + (0.405 * Smoker) + (0.102 * ln(HSCRP)) + (0.541 * PrematureParentalMI) - 33.097
TenYearRisk = 100 * (1 - 0.8990e(Terms))

 
Input:
 
Age  
Systolic Blood Pressure  
Total Cholesterol  
HDL Cholesterol  
HS CRP  
Smoker No (0)

Yes (1)
Premature Parental MI No (0)

Yes (1)
Results:
 
Terms  
Ten Year Risk  
 
Decimal Precision:

 
   
 

 
Notes

 
References
  1. Lee KK, Hlatky MA. ACP Journal Club. Reynolds Risk Score for men predicted cardiovascular events more accurately than traditional risk factors only. Ann Intern Med. 2009 Mar 17;150(6):JC3-14. PMID: 19306496 PubMed Logo
  2. Ridker PM, Paynter NP, Rifai N, et. al. C-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds Risk Score for men. Circulation. 2008 Nov 25;118(22):2243-51, 4p following 2251. doi: 10.1161/CIRCULATIONAHA.108.814251. Epub 2008 Nov 9. PMID: 18997194 PubMed Logo
  3. DeFilippis AP, Young R, Carrubba CJ, et. al. An analysis of calibration and discrimination among multiple cardiovascular risk scores in a modern multiethnic cohort. Ann Intern Med. 2015 Feb 17;162(4):266-75. PMID: 25686167 PubMed Logo
  4. Ridker PM, Cook NR. Comparing cardiovascular risk prediction scores. Ann Intern Med. 2015 Feb 17;162(4):313-4. PMID: 25686171 PubMed Logo

 
Associated Medical Subject Headings [MeSH] Terms
 
         80 and over, Aged, American Heart Association, Antihypertensive Agents, Aspirin, Biological Markers, C-Reactive Protein, Calibration, Cardiovascular Diseases, Coronary Artery Disease, Diabetes Complications, Female, Follow-Up Studies, Humans, Hypolipidemic Agents, Inflammation, Life Style, Likelihood Functions, Male, Middle Aged, Myocardial Revascularization, Platelet Aggregation Inhibitors, Practice Guidelines as Topic, Predictive Value of Tests, Primary Prevention, Prospective Studies, Risk Assessment, Sex Characteristics, Voluntary Health Agencies

 
Associated Logical Observation Identifiers Names and Codes [LOINC]
 
Parameter LOINC's and Units
Age 21612-7 : Years old      21612-7 : yr      21612-7 : years      30525-0 : Years old      30525-0 : yr      30525-0 : years      
Total Cholesterol 2093-3 : mg/dL      14647-2 : mmol/L      
HDL Cholesterol 2085-9 : mg/dL      14646-4 : mmol/L      

 
This material contains content from LOINC® (http://loinc.org). The LOINC table, LOINC codes, and LOINC panels and forms file are copyright © 1995-2014, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and available at no cost under the license at http://loinc.org/terms-of-use.

 
Associated ICD9-CM Codes
 
   401Essential hypertension
   401.1Benign hypertension
   272.2Mixed hyperlipidemia
   272.4Hyperlipidemia nec/nos
   414.0Coronary atherosclerosis
   414.4Coronary atherosclerosis

 
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