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  Polycythemia Vera Diagnostic Criteria

 

Diagnostic : 2 Group A and 1 Group B and 0 Group C

Diagnostic : 2 Group A and 0 Group B and 2 Group C
 
Group A
      Elevated RBC mass
      Males: ≥36 mL/kg
      Females: ≥32 mL/kg
      Arterial O2 saturation ≥92%
Group B
      Splenomegaly
Group C
      Platelet count >400,000/microL
      WBC count >12,000/microL in the absence of fever or infection
      Leukocyte alkaline phosphatase (LAP) score >100 in the absence of fever or infection
      B12 >900 pg/mL or serum unbound B12-binding capacity >2200 pg/mL

 

 
     
 
Include literature references: Yes   No

 

 
References
  1. Berk PD, Goldberg JD, Donovan PB, et. al. Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols. Semin Hematol. 1986 Apr;23(2):132-43. PMID: 3704665 PubMed Logo

 
Associated Medical Subject Headings [MeSH] Terms
 
         Acute Disease,   Age Factors,   Bloodletting,   Chlorambucil,   Combined Modality Therapy,   False Positive Reactions,   Follow-Up Studies,   Gastrointestinal Neoplasms,   Gout,   Hematocrit,   Humans,   Hydroxyurea,   Leukemia,   Phosphorus Radioisotopes,   Platelet Aggregation,   Platelet Count,   Polycythemia Vera,   Prospective Studies,   Pruritus,   Skin Neoplasms,   Thrombosis

 
Associated ICD10-CM Codes
 
   D75.1Secondary polycythemia
   D45Polycythemia vera

 
Associated ICD9-CM Codes
 
   238.4Polycythemia vera
   289.0Secondary polycythemia

 
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