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  Atrial Fibrillation CHADS(2) Score for Stroke Risk

 

Diagnosed heart failure, past or current (1 point)

Hypertension treated or untreated (1 point)

Age ≥75 years (1 point)

Diabetes Mellitus (1 point)

Secondary prevention in patients with prior ischemic stroke, TIA or thromboembolism (2 points)

 
Total Criteria Point Count:
 
     

 
  Stroke Risk per 100 Person Years/Warfarin Rx Interpretation

 
0 Points: 0.25 ON Rx; 0.49 NO Rx
1 Point: 0.72 ON Rx; 1.52 NO Rx
2 Points: 1.27 ON Rx; 2.50 No Rx
3 Points: 2.20 ON Rx; 5.27 NO Rx
4 Points: 2.35 ON Rx; 6.02 NO Rx
5 to 6 Points: 4.60 ON Rx; 6.88 NO Rx

 

 
References
  1. Gage BF, Waterman AD, Shannon W, et. al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001 Jun 13;285(22):2864-70. PMID: 11401607 PubMed Logo
  2. Go AS, Hylek EM, Chang Y, et. al. Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trials translate into clinical practice?. JAMA. 2003 Nov 26;290(20):2685-92. PMID: 14645310 PubMed Logo
  3. MedCalc CrossRef: Atrial Fibrillation CHA(2)DS(2)-VASc Score for Stroke Risk
  4. Cairns JA. ACP journal club. CHA2DS2-VASc had better discrimination than CHADS2 for predicting risk for thromboembolism in atrial fibrillation. Ann Intern Med. 2011 May 17;154(10):JC5-13. doi: 10.1059/0003-4819-154-10-201105170-02013. PMID: 21576531 PubMed Logo
  5. Olesen JB, Lip GY, Hansen ML, et. al. Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study. BMJ. 2011 Jan 31;342:d124. doi: 10.1136/bmj.d124. PMID: 21282258 PubMed Logo
  6. Wild D. ACP Journal Club. CHADS2 score predicted bleeding and death in atrial fibrillation treated with anticoagulants. Ann Intern Med. 2012 Apr 17;156(8):JC4-13. doi: 10.1059/0003-4819-156-8-201204170-02013. PMID: 22508753 PubMed Logo
  7. Oldgren J, Alings M, Darius H, et. al., RE-LY Investigators. Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: a subgroup analysis of the RE-LY trial. Ann Intern Med. 2011 Nov 15;155(10):660-7, W204. doi: 10.1059/0003-4819-155-10-201111150-00004. PMID: 22084332 PubMed Logo

 
Associated Medical Subject Headings [MeSH] Terms
 
         80 and over,   Aged,   Anticoagulants,   Antithrombins,   Atrial Fibrillation,   Benzimidazoles,   Case-Control Studies,   Cause of Death,   Cohort Studies,   Comorbidity,   Female,   Hemorrhage,   Hospitalization,   Humans,   Kaplan-Meier Estimate,   Male,   Middle Aged,   Proportional Hazards Models,   Randomized Controlled Trials as Topic,   Risk,   Risk Assessment,   Risk Factors,   Severity of Illness Index,   Stroke,   Survival Analysis,   Thromboembolism,   Vitamin K,   Warfarin,   beta-Alanine

 
Associated ICD9-CM Codes
 
   427.31Atrial fibrillation
   437.9Cerebrovasc disease nos

 
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